Titanium, Vanadium and Chromium Transition Metal Schiff Base Complexes with Biological, Catalytic, and Anti-Glycation Activities: A Review

 Schiff bases are chemicals formed when a primary amine and an aldehyde or ketone react together. To generate Schiff base complexes, they can be coordinated with metals, particularly transition metals. The following are the study objectives for this project: To begin, we’ll go over the synthesis, characterisation, and biological activities of both Schiff base ligands and their titanium, vanadium, and chromium transition metal complexes. Second, studies of the catalytic activities of Schiff base ligands and their transition metal complexes of titanium, vanadium, and chromium are being investigated. Finally, the anti-glycation properties of aroyl-hydrazine ligands, their chromium (III) complexes, and the metal salt itself will be discussed. The references were found using the internet as a source of information. Antibacterial and antifungal biological activity were primarily considered in this analysis. Both gramme positive and gramme negative strains were explored for the antibiotic. The study’s findings revealed that several researchers investigated antibacterial capabilities against bacteria, fungi, and anti-tumour activity against breast cancer using Schiff base complexes, Schiff bases, and metal ions for the metals titanium, vanadium, and chromium. Metal ions have a lower inhibitory capacity than ligands, while complexes have the highest inhibition capacity against microbes, according to antimicrobial literature research. MCF-7 (breast cancer) cells were treated with mono- and dioxide-vanadium (V) complexes, which displayed anticancer action. The catalytic activity of cis-Dioxido vanadium (V) complexes on the oxidation of cyclohexane was also examined, and conversion of 12 percent and selectivity of up to 85 percent were obtained. Introduction, methods for locating references, results and discussion, acknowledgements, and references are the five sections of the work. When evaluated as antimicrobial agents, the Schiff base complexes outperformed their ligands, according to the findings of the review. When the complexes were tested for catalytic activity on organic chemistry reactions, they likewise performed well. When compared to amino group complexes, chromium (III)-aroyl-hydrazine complexes were found to be more effective at inhibiting protein glycation.

Author(s) Details:

Gervas E. Assey,
Chemistry Unit, Department of Natural Sciences and Information Technology, Faculty of Science, Mwenge Catholic University, Tanzania.

Raphael Mgohamwende,
Chemistry Unit, Department of Natural Sciences and Information Technology, Faculty of Science, Mwenge Catholic University, Tanzania.

Please see the link here: https://stm.bookpi.org/NICB-V8/article/view/6283

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