Therapeutic Properties of Mesenchymal Stem Cell on Organ Ischemia-reperfusion Injury: A Review
The scarcity of organ donors is a big global issue. Organ failure necessitates the use of functional organ transplants. Organs are kept for varying periods of warm and cold ischemia time, which necessitates their placement in a preservation device. The organs are damaged during ischemia and reperfusion due to a lack of oxygen during the ischemia step and oxidative stress during the reperfusion step. To avoid or reduce the severity of injuries, many approaches have been created. Cold static preservation solutions, which comprise the inclusion of numerous chemical compounds, were initially created to maximise cold static preservation. Injuries to the organ Mesenchymal stem cells (such as bone marrow stem cells, adipose-derived stem cells, and umbilical cord stem cells) have been shown to be effective in the healing of damaged organs. The use of bone marrow stem cells, adipose-derived stem cells, and umbilical cord stem cells to prevent or reduce ischemia-reperfusion damage will be the focus of this review.
Author (s) Details
Clinical Research Department, Emmaus Medical, Torrance, CA 90503, USA.
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