A Brief Study of Natural Drug Camptothecin
The natural alkaloid 20-(S)-Camptothecin (CPT) is derived from the bark of the Camptotheca acuminata tree (Chinese happy tree). It works as a DNA topoisomerase 1 toxin with intriguing anticancer properties, but its application is restricted due to low stability and unexpected drug-drug interactions. It has been widely employed in cancer therapy since the late twentieth […]