Tag: Camptothecin

Determining the Effect of siRNA-Egr-1 and Camptothecin on Growth and Chemosensitivity of Breast Cancer Cells

In the research, the breast cancer container lines SK-BR3 and MCF-7 were used to explore the belongings of a siRNA targeting the Egr-1, either alone or in addition to the breast tumor treatment camptothecin (Cpt), in reducing conscience cancer cell continuation and anchorage-liberated growth.. Cancer is a global energy problem being the reason for one […]

A Brief Study of Natural Drug Camptothecin

The natural alkaloid 20-(S)-Camptothecin (CPT) is derived from the bark of the Camptotheca acuminata tree (Chinese happy tree). It works as a DNA topoisomerase 1 toxin with intriguing anticancer properties, but its application is restricted due to low stability and unexpected drug-drug interactions. It has been widely employed in cancer therapy since the late twentieth […]

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