Systemic Lupus Erythematosus: A Review


Systemic lupus erythematosus (SLE) is a chronic, multisystemic, heterogeneous autoimmune disease. Systemic lupus erythematosus can affect any tissues, organs, or even entire systems because it is a multisystem illness. Lupus comes in a variety of forms, such as cutaneous lupus erythematosus (CLE), which affects the skin and results in a malar rash, discoid lupus erythematosus (DLE), which affects one or more internal organs, and systemic lupus erythematosus. The damage is brought on by immune complex deposition as well as inflammation brought on by direct antibody responses to biological tissues. In addition to counselling and raising awareness, glucocorticoids, immunosuppressants, and anti-malarials are the combo treatment used to treat SLE. SLE is the most common kind of lupus erythematosus, and women are six times more likely than males to have it. People of all ages are afflicted, but women between the ages of 20 and 45 are the ones who are most frequently impacted. Chronic and acute inflammation of different bodily parts is a hallmark of the autoimmune illness lupus. When the body’s own immune system attacks its own tissues, autoimmune disorders result.

Author(s) Details:

Nasrin Habib,
Department of Physiology, Quest International University, Malaysia.

Sellaiah S. Pillay,
Consultant Radiologist, Quest International University, Malaysia Quest International University, Malaysia.

Tahmina Afrose,
Department of Community Medicine AIMST University FOM; AIMST University; Malaysia.

Mamunur Rashid,
Department of Medicine, Quest International University, Malaysia.

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