Study on Reproductive Disorders in Patients with Metabolic Syndrome and Obesity: Pathogenesis, Clinical Manifestations and Prevention

The rising prevalence of metabolic syndrome (MetS) has drew the attention of medical researchers. MetS aetiology, effects, and prevention must all be researched in order to better medical care for patients with this disease, which is also a major societal issue. The goal of the study is to uncover the underlying causes of reproductive abnormalities in patients with metabolic syndrome, as well as the impact of lifestyle in preventing bad reproductive outcomes. Methods: Contextual searches were conducted in the Cochrane Library, PubMed, and WHO recommendations as well as the advice of key European and American associations on the management of individuals with diabetes. The pathophysiology, clinical symptoms, consequences, and prevention of reproductive problems and infertility in MetS and obese patients were investigated. Reduced testosterone levels, decreased sperm fertility, and erectile dysfunction were reported to be the most common reproductive problems in males with MetS. Metabolic problems in women with MetS can result in infertility, menstrual irregularities, premature birth, and births of children with congenital defects. Conclusions: Reproductive difficulties in MetS patients might have significant effects for people, such as decreased quality of life, depression, and an increase in metabolic illnesses, as well as for countries, such as population loss. Exercise and a diet that normalises basal metabolic rate improve reproductive health in MetS patients. Despite the demonstrated benefits of lifestyle changes, the hunt for the optimal treatment for MetS patients’ reproductive issues continues.           

Author (s) Details

O. Yelizarova

SI “O.M. Marzieiev Institute for Public Health, NAMSU, Ukraine.

E. Omelchenko
SI “O.M. Marzieiev Institute for Public Health, NAMSU, Ukraine.
B. Nykula
Kyiv Clinical Hospital on Railways Transport №2 of the Health Centre of JSC “Ukrainian railways”, Ukraine.

O. Lynchak
SI “O.M. Marzieiev Institute for Public Health, NAMSU, Ukraine.

O. Procuk
Shupyk National Healthcare University of Ukraine.

O. Polka
SI “O.M. Marzieiev Institute for Public Health, NAMSU, Ukraine.

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