Study on Defensive Mechanism of Respiratory System


The purpose of this article is to outline the various components that make up the respiratory system’s defence systems. Mechanical barrier phenomena, humoral substances, and cells from both the innate and particular adaptive immune responses are all part of the respiratory system’s defence. The barrier mechanisms and the innate immune response are the first line of lung protection. Dendritic cells (DC) interact with infections and antigens by transmitting information to lymph nodes in the lungs, which results in an adaptive immune response. DCs connect the innate and adaptive immune responses in this way. The adaptive immune response is targeted by antibodies and particular T cells that work together in a synergistic and coordinated manner. Furthermore, immunological memory is formed. The ability to control immune response by improving protection mechanisms (e.g. vaccinations, immunostimulants) or lowering allergy, autoimmune, or chronic inflammatory illnesses of the respiratory system has been made possible by understanding these pathways (eg. corticosteroids, biologics).

Author (S) Details

Arnoldo Quezada
Department of Pediatrics, School of Medicine, University of Chile, Santiago, Chile.

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