Simultaneous Isolation of Chryseobacterium gleum from a Case of Blood Stream Infection and Pneumonia: A Rare Isolate

Chryseobacterium gleum is a gram-negative, non-fermentative pathogen with catalase and oxidase activity that is becoming a multidrug-resistant pathogen in health-care settings, particularly in cases of bloodstream infection, urinary tract infection, and pneumonia. Only a few Chryseobacterium species have been identified so far. Given the high mortality rates associated with these pathogens, quick and accurate identification methods are critical for improving patient care. We present a case of bloodstream infection and pneumonia in a 60-year-old female patient with k/c/o CKD/ Type 2 DM/ HTN/ CAD who was admitted to the emergency room with a high-grade fever. For the past ten days, I’ve been suffering from shortness of breath, and for the last three days, I’ve been out of breath. Chryseobacterium gleum was isolated from two paired blood cultures and an ET culture with identical susceptibility patterns for Cephalosporins, Carbapenems, and Colistin, as well as susceptibility to Levofloxacin, Cotrimoxazole, and Minocycline. The patient’s clinical condition improved after starting on Levofloxacin. Extraction of a rare isolate called Chryseobacterium gleum from both the bloodstream and the lower respiratory tract at the same time is extremely rare. Because of the inherent resistance to Carbapenems and Colistin, early laboratory detection is required to guide effective antibiotic therapy, thereby reducing the risk of health-care-associated infections.

Author (S) Details

Dr. M. Shabnum
Department of Microbiology, Narayana Medical College, Nellore, Andhra Pradesh, India.

P. Sreenivasulu Reddy
Department of Microbiology, Narayana Medical College, Nellore, Andhra Pradesh, India.

P. Vasundhara
Department of Microbiology, Narayana Medical College, Nellore, Andhra Pradesh, India.

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