Press Release on Bioinformatics Research: September-2018

Bioinformatics software developed to predict the effect of cancer-associated mutations

A new piece of computer code has been developed that analyses mutations in proteins. These mutations square measure potential inducers of diseases adore cancer. the event is free, easy, versatile and, above all, quick bioinformatics application that’s capable of analyzing and mixing the data from forty,000 proteins inside the area of 1 minute. [1]

RNA sequencing and bioinformatics analysis of the long noncoding RNA–mRNA network in colorectal cancer

Long noncoding ribonucleic acid (lncRNA) plays a vital restrictive role in tumorigenesis. This study aims to research the lncRNA–messenger ribonucleic acid (mRNA) expression network and potential roles in large intestine cancer (CRC). The lncRNA expression profile was analyzed in CRC tissue by ribonucleic acid sequencing and therefore the functions of differentially expressed genes were analyzed by sequence metaphysics (GO) and city cyclopedia of Genes and Genomes (KEGG). The lncRNA‐mRNA network was predicted with bioinformatics. From the result, we have a tendency to known 485 differential expression lncRNAs and 2383 mRNAs in CRC, GO, and KEGG analyses showed that the changes in lncRNAs were in the main related to metabolism and transcription regulation that were totally different from RNA operate. [2]

The Microbial Ecosystem of Beer Spoilage and Souring: Competition and Cooperation in the Age of Bioinformatics

The production business generates $350 billion in revenue within the U.S. annually, representing one.9% of the gross domestic product. Spoilage may be a persistent drawback throughout production and distribution that causes economic loss, and is thus meticulously avoided. Contrarily, artisanal bitter beers are essentially created by a various kind of these spoilage organisms metabolically interacting in interdependency as a microorganism scheme. [3]

MOLGENIS Research: Advanced bioinformatics data software for non-bioinformaticians

Motivation: the degree and quality of biological information will increase apace. several clinical professionals and medical specialty researchers while not a bioinformatics background are generating huge ’-omics’ information, however, don’t invariably have the tools to manage, method or publically share this information. [4]

Impact of Bioinformatics Tools in Genomic Biomedicine

Bioinformatics is associate degree knowledge base field that develops ways and computer code tools for understanding biological information. This paper was borne from the actual fact that some medical laboratories and connected fields have didn’t implement Bioinformatics tools as they relate to Genomic medical specialty experiments. The paper thus seeks to review the extent of this involvement and additionally give ways and resource reports which will give novel info on technological tools that may be of interest to a broad audience within the space of Bioinformatics and Genomic analysis. [5]

Reference

[1] Bioinformatics software developed to predict the effect of cancer-associated mutations

Date: June 30, 2016, Source: University of the Basque Country (web link)

[2] RNA sequencing and bioinformatics analysis of the long noncoding RNA–mRNA network in colorectal cancer

Zhang Z, Jia H, Gu T, Hu Q, Yu J, Zang D, Song N, Wang H. RNA sequencing and bioinformatics analysis of the long noncoding RNA–mRNA network in colorectal cancer. Journal of cellular biochemistry. 2018 Aug 26. (web link)

[3] The Microbial Ecosystem of Beer Spoilage and Souring: Competition and Cooperation in the Age of Bioinformatics

Kettering A. The Microbial Ecosystem of Beer Spoilage and Souring: Competition and Cooperation in the Age of Bioinformatics. (web link)

[4] MOLGENIS Research: Advanced bioinformatics data software for non-bioinformaticians

van der Velde KJ, Imhann F, Charbon B, Pang C, van Enckevort D, Slofstra M, Barbieri R, Alberts R, Hendriksen D, Kelpin F, de Haan M. MOLGENIS Research: Advanced bioinformatics data software for non-bioinformaticians. Bioinformatics. 2018 Aug 27. (web link)

[5] Impact of Bioinformatics Tools in Genomic Biomedicine

Ekwonwune Emmanuel Nwabueze1* and E. Obiukwu Charles2*

1Department of Computer Science, Imo State University, Owerri, Nigeria.

2Department of Microbiology, Imo State University, Owerri, Nigeria. (web link)

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