Prescribing Pattern of Antidiabetic Drugs amongst Pre-obese Diabetic Patients in a Tertiary Care Hospital, India

Background: In order to improve prescription quality and promote logical prescribing patterns, it is unavoidable to look into the elements that influence doctors’ prescribing habits. Prescribers can benefit from feedback on drug prescription and consumption patterns in order to enhance their prescribing behaviour. Diabetes is a non-communicable disease that affects many people. Due to the condition and its various complications, such as CAD, hypertension, renal difficulties, retinal damage, neurological abnormalities, and generalised infections, it has a significant morbidity and mortality rate. The treatment is customised and neither full nor satisfying, given the multifactorial background of high prevalence, progressive nature of the disease, and availability of many therapeutic regimens offered on a trial and error basis.

The goal of this study was to examine the present prescribing pattern in pre-obese type 2 diabetes mellitus patients in terms of drug/drugs per prescription, dose, treatment duration, and frequency of drug changes.

Methods: Between 2014 and 2016, a prospective, parallel group, comparative observational study was conducted in the department of pharmacology and endocrinology at KIMS Bhubaneswar. The pre-obese individuals were separated into two groups: a) new diabetics and b) old diabetics (3 years). a)Monotherapy-Metforminb)Combination therapy-Metformin+another antidiabetic group, especially sulfonylureas, alphaglucosidase inhibitors, or DPP 4 inhibitors c)Triple therapy(Metformin+SU+Voglibose or Gliptins or Glitazones) d)Insulin with additional oral hypoglycemic medicines

The majority of prescriptions in this tertiary care hospital were determined to be in compliance with the ADA criteria, according to the results of the prescribing pattern analysis. As a first-line treatment, metformin monotherapy was prescribed. Sulphonylureas/Gliptins/Alpha glucosidase inhibitors/thiazolidinediones were utilised as a second-line therapy or as monotherapy, depending on the patient’s needs, tolerance, and cost.

Conclusions: The anti-diabetic drugs provided at this hospital were determined to be compliant with the American Diabetes Association’s (ADA) guidelines.

Author(S) Details

Sougata Sarkar
Department of Clinical and Experimental Pharmacology, School of Tropical Medicine, Kolkata, India.

Vartika Srivastava
2Department of Pharmacology, Kalinga Institute of Medical Sciences, Bhubaneswar, India.

Adrija Roy
Community Medicine, KIMS, Bhubaneswar, India.

Manjushree Mohanty
Kalinga Institute of Medical Sciences, Bhubaneswar, Odisha, India.

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