Oral Cavity – A Potential Repository for Early Detection of SARS-CoV-2 Infection in Asymptomatic Carriers

The new Corona Virus Disease 2019 (COVID-19) epidemic has become a worldwide health emergency. The early diagnosis and successful isolation of patients is the key cause of concern among the health authorities, as the present influenza is very close to the old common flu in its initial clinical appearance. Real Time Reverse Transcription Polymerase Chain Reaction (rRTPCR) is currently considered to be the gold standard for the identification of the causative virus, SARS-Cov-2, but in the meantime, it takes time and poses the risk of further spread to the exposed individuals , especially healthcare staff. Social distancing is also the only way known worldwide to avoid the spread of the disease and to keep isolating, screening and acting on individuals with clinical symptoms. Asymptomatic carriers, however, are the next point of concern and need mass screening that is not feasible with rRT-PCR per se. Researchers are trying to create a way out for the Detection of the SARS-Cov-2 virus in asymptomatic carriers or in patients who are incubated, thereby eradicating the spread of the disease and flattening the virus multiplication curve. As stated in the literature on salivary research, early detection of a related virus during the outbreak of SARS was found to be encouraging. This paper is an attempt to emphasise that, due to its anatomical relationship with the salivary glands, naso-oro-pharynx, and the mucosa that are gradually filled with saliva, the oral cavity may be a possible reservoir of SARS-CoV-2 both in the incubation process and/or convalescence time. Samples of saliva are easy to obtain and possibly make it an excellent method for mass screening, thereby promoting the early detection and prevention of further spread of the deadly From a pandemic.

Author (s) Details

Dr. Anmol Agarwal
Department of Oral and Maxillofacial Surgery, Institute of Dental Studies and Technologies, Modinagar, Ghaziabad, Uttar Pradesh, India.

Dr. Gaurav Mittal
Department of Oral and Maxillofacial Surgery, Institute of Dental Studies and Technologies, Modinagar, Ghaziabad, Uttar Pradesh, India.

Dr. Payal Agarwal
Department of Oral, Dental and Craniofacial Care, Yashoda Super Specialty Hospital, Kaushambi, Ghaziabad, Uttar Pradesh, India

Dr. Shimona Raj Mittal
Private Practitioner, Tooth Tamers the Family Dentists, Govindpuram, Ghaziabad, Uttar Pradesh, India.

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