Latest Research News on Left Ventricular: Jan – 2020

Echocardiographic assessment of left ventricular hypertrophy: Comparison to necropsy findings

To determine the accuracy of echocardiographic left ventricular (LV) dimension and mass measurements for detection and quantification of LV hypertrophy, results of blindly read antemortem echocardiograms were compared with LV mass measurements made at necropsy in 55 patients. LV mass was calculated using M-mode LV measurements by Penn and American Society of Echocardiography (ASE) conventions and cube function and volume correction formulas in 52 patients. [1]

Left ventricular fibre architecture in man.

In order to research the likelihood of regional variation of ventricular structure, 25 normal postmortem human hearts were studied by inspection of cavity shape and subepicardial fibre orientation, by dissection, and by the histology of sections in two orthogonal planes. Ventricular architecture was complex. Inlet and outlet long axes were separated by 30 degrees within the ventricle . within the right the corresponding figure was 90 degrees. The thickest a part of the left ventricular wall was at the bottom . At the apex there was potential endo- and epicardial continuity. Left ventricular cavity shape departed significantly from any simple geometric figure, there being, consistently, regions of both positive and negative curvature on the diaphragmatic aspect. The presence of trabeculae caused considerable variation in wall thickness. [2]

Left ventricular fibre architecture in man.

In order to research the likelihood of regional variation of ventricular structure, 25 normal postmortem human hearts were studied by inspection of cavity shape and subepicardial fibre orientation, by dissection, and by the histology of sections in two orthogonal planes. Ventricular architecture was complex. Inlet and outlet long axes were separated by 30 degrees within the ventricle . within the right the corresponding figure was 90 degrees. The thickest a part of the left ventricular wall was at the bottom . At the apex there was potential endo- and epicardial continuity. Left ventricular cavity shape departed significantly from any simple geometric figure, there being, consistently, regions of both positive and negative curvature on the diaphragmatic aspect. The presence of trabeculae caused considerable variation in wall thickness. Striking variation was found within the arrangement of subepicardial muscle fibres. [3]

Associations between echocardiographic findings and prospective changes in residual renal function in patients new to peritoneal dialysis

Although echocardiograms are often performed when peritoneal dialysis is started, associations between commonly reported findings and prospective changes in renal function remain understudied. Ninety-nine of 101 patients within the Trio Trial had transthoracic echocardiograms within 6 months of dialysis initiation, and measurements of residual renal function every six weeks for up to 2 years. Generalized mixed modelling rectilinear regression in STATA was wont to examine associations between left atrial size, left ventricular hypertrophy, left ventricular ejection fraction, right ventricular blood pressure , and left valvular calcification with subsequent slopes in renal function. [4]

Use of Levosimendan in Patients With Low Left Ventricular Ejection Fraction in Ordu/Turkey: Report of Experience with Mini Review

Aims:To report the effect of prophylactic usage of levosimendan in patients with low left ventricular ejection fraction undergoing arteria coronaria bypass grafting (CABG).

Methods: We reported early results of 32 patients (26 male and 6 female; mean age 61.630 ± 9.653 years) who received preoperative levosimendan who underwent CABG with left ventricular ejection fraction (LVEF) of 35% or less between March 2014 and August 2016. [5]

Reference

[1] Devereux, R.B., Alonso, D.R., Lutas, E.M., Gottlieb, G.J., Campo, E., Sachs, I. and Reichek, N., 1986. Echocardiographic assessment of left ventricular hypertrophy: comparison to necropsy findings. The American journal of cardiology, 57(6), (Web Link)

[2] Greenbaum, R.A., Ho, S.Y., Gibson, D.G., Becker, A.E. and Anderson, R.H., 1981. Left ventricular fibre architecture in man. Heart, 45(3), (Web Link)

[3] Greenbaum, R.A., Ho, S.Y., Gibson, D.G., Becker, A.E. and Anderson, R.H., 1981. Left ventricular fibre architecture in man. Heart, 45(3), (Web Link)

[4] Associations between echocardiographic findings and prospective changes in residual renal function in patients new to peritoneal dialysis
Sara Mahdavi, Kibar Yared, George Wu, Billy Omar, Dinesh Savundra, Gordon Nagai, Edgar Hockmann, Anton Svendrovski, Antonio Bellasi, Paul Tam & Tabo Sikaneta
Scientific Reports volume 9, (Web Link)

[5] Yalcin, M., Godekmerdan, E., Derya Tayfur, K., Yazman, S. and Ozyazicioglu, A. (2017) “Use of Levosimendan in Patients With Low Left Ventricular Ejection Fraction in Ordu/Turkey: Report of Experience with Mini Review”, Cardiology and Angiology: An International Journal, 6(2), (Web Link)

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