Inflammatory Markers in Critically Ill Patients with Venous Thrombosis: A Cross-Sectional Study in a Tertiary Hospital

Vein thrombosis is a serious public health problem that has a considerable human and economic cost in the United States. In hospitalised patients, venous thrombosis is a leading cause of morbidity and mortality, and it is potentially preventable. Over the last decade, deep vein thrombosis (DVT) has grown in popularity as a potentially preventable cause of morbidity and mortality in hospitalised patients. The researchers wanted to investigate inflammatory indicators in venous thrombosis.

Materials and Procedures: Patients admitted to tertiary hospitals were studied in a cross-sectional research. The study examined 59 cases of venous thrombosis that were confirmed by radiography. Written informed consent was obtained for participation in the study and the conduct of investigations. Between November 2017 and September 2019, the study was conducted.

Results: The average age of the study participants was 43.6 years (SD=16.4), with a range of 20 to 72 years. Among the 59 cases, 48 were males (81.4%) and 11 were girls (18.6 percent). The patients’ average Body Mass Index was 24.33 2.84 kg/m2. CRP levels were increased in 48 of the 59 individuals (81.3%). Serum homocysteine levels were increased in 46 individuals (77%) (>15 mol/L). Low HDL was found in 74.6 percent of the 59 participants, whereas high LDL was found in 61 percent and high Triglycerides was found in 45 percent. The level of total cholesterol has risen by 40.7 percent. D dimer levels were found to be high in 98.3% of the cases.

Conclusion: We discovered that spontaneous venous thrombosis is a common cause of worry among men aged 20 to 29, who have a BMI of more than 25 kg/m2. Inflammatory markers were found to be significantly greater in venous thrombosis patients.

Author(S) Details

Shaheen B. Shaikh
Department of Biochemistry, Yenepoya Medical College Hospital, Mangaluru, Karnataka, India.

H. M. Ismail
Department of Critical Care Medicine, Yenepoya Medical College Hospital, Mangaluru, Karnataka, India.

R. Bhavya
MVJ Medical College and Research Hospital, Hoskote Taluk, Bangalore Rural, India.

P. Ganesh
Department of Biochemistry, Yenepoya Medical College Hospital, Mangaluru, Karnataka, India.

Sarfaraz Shaikh
Department of Emergency Medicine, DM WIMS Medical College Wayanad, Kerala, India.

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