Incidence of Scrub Typhus in a Tertiary Care Hospital in Kolkata, India: A Cross-sectional Study Approach

Scrub typhus is a disease caused by Orientia tsutsugamushi and spread by trombiculid mites in India. In India, it is a common cause of acute febrile sickness. Fever, headache, myalgia, and GI symptoms are common signs and symptoms, and it’s usually coupled with a morbilliform rash (40 percent) and eschar (50 percent) caused by the mite’s bite. In the early stages of disease, abnormal LFTs and lymphocytosis are prevalent. It’s commonly referred to as PUO. Early diagnosis and treatment results in a high rate of complete recovery.

The goal of this study was to bring attention to the prevalence of scrub typhus at a tertiary care hospital in Kolkata, India.

From May to December 2019, the authors assessed 100 individuals who had a fever, malaise, headache, with or without rash, for more than a week. Fever profiles (Dengue NS1 antigen, MP, MPDA, TyphidotM) and cultures were performed as part of routine blood tests. Patients with lymphocytosis, hyponatremia, and transaminitis who had no known cause of fever were tested for Scrub typhus using indirect immunofluorescence and IgM antibody detection.

Using the aforementioned procedure, a total of 22 patients were found to be positive for scrub typhus (22 percent ). Male: Female ratio was 3:4 (9 vs 12). (9 vs 12). Patients ranged in age from 16 to 76 years old. Almost all patients diagnosed with Scrub Typhus had lymphocytosis, hyponatremia, and transaminitis as primary symptoms.

Conclusions: Clinicians will be more likely to suspect scrub typhus in unexplained febrile patients after reading this study. In clinical studies, a younger patient population, fast diagnosis, and prompt treatment have been linked to a shorter disease course and better result.

Author(S) Details

Kausik Munsi
Department of Medicine, KPC Medical College and Hospital, Kolkata, West Bengal, India.

Sayonee Das
Department of Medicine, KPC Medical College and Hospital, Kolkata, West Bengal, India.

Ramiz Islam
Department of Medicine, KPC Medical College and Hospital, Kolkata, West Bengal, India.

Parvez Shahide Biswas
Department of Medicine, KPC Medical College and Hospital, Kolkata, West Bengal, India.

Satyabrata Ganguly
Department of Medicine, KPC Medical College and Hospital, Kolkata, West Bengal, India.

Mayur Bahan Mukherji
Department of Medicine, KPC Medical College and Hospital, Kolkata, West Bengal, India.

View Book:- https://stm.bookpi.org/NHMMR-V1/article/view/6185

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