Due to their extensive range of biological roles and high degree of pharmacological efficacy, quinoline alkaloids are a significant family of heterocyclic chemicals. N-methylaniline and 1-bromo-3-methyl-2-butanone were used to create an elegant and complete synthesis of the quinoline alkaloid orixiarine. This study paves the way for the production of fresher orixiarine derivatives for inquiry in a variety of upcoming biological investigations.

Author(s) Details:

T. Suresh,
Department of Chemistry, Bharathiar University, Coimbatore, India.

K. Velmurugan,
Department of Applied Chemistry, Karunya Institute of Technology and Sciences (Deemed to be University), Karunya Nagar, Coimbatore, India.

P. S. Mohan,
Department of Chemistry, Bharathiar University, Coimbatore, India.

R. Nandhakumar,
Department of Applied Chemistry, Karunya Institute of Technology and Sciences (Deemed to be University), Karunya Nagar, Coimbatore, India.

Please see the link here: https://stm.bookpi.org/CTCB-V4/article/view/7808

Keywords: N-methylaniline, 1-Bromo-3-methyl-2-butanone, orixiarine, total synthesis