Latest News on Alloxan: September 2021
Effect of aloes on blood glucose levels in normal and alloxan diabetic mice The acute and chronic effects of the exudate of Aloe barbadensis leaves and its bitter principle were studied on plasma glucose levels of alloxan-diabetic mice. Aloes was administered orally, 500 g/kg, and the bitter principle was administered intraperitoneally, 5 mg/kg. The […]
Study on Potential Drug Interactions between cART and New Psychoactive Substances
The European illicit drug market is being flooded by new dangerous substances with unknown synthetic chemical structures or structures of identified companies that have been modified to escape prosecution. Over the past few years, hundreds of synthetic cannabinoids, synthetic phenylethylamine / cathinones or drugs of very uncommon occurrence have been confiscated by the authorities, which […]
Highlighting New Antiretrovirals on the Block: Pharmacological News from CROI 2017
Several new drugs for the treatment of HIV / AIDS were presented at the Conference on Retrovirus and Opportunistic Infections (CROI) 2017 in Seattle, USA. This analysis shows the most promising candidates and addresses the mechanism of action of new integrase strand inhibitors (INSTI), nucleoside (NRTI) and non-nucleoside reverse transcriptase (NNRTI) as well as protease […]
Glycemic Index Profiling of Raw and Germinated Quinoa (Chenopodium quinoa Willd)
Quinoa contains high biological value proteins, low glycemic index carbohydrates and ⁇ -3 and 6 fatty acid phytosteroids that have health benefits. The key benefit of quinoa is that it meets the rising international demand for gluten-free products in cakes , pastries, pasta and baked goods, along with being a protein substitute in the flour […]
An Overview on Nano Drug Delivery: Challenges and Its Safety Issues
The science and technology of precisely controlling the structure of matter at the molecular level is nanotechnology. It is the use of matter and its manipulation on a small scale. At this size, atoms and molecules behave differently and have a number of fascinating and unexpected uses. By manipulating matter on the nanometer length scale […]
Recent Advancements of High-Performance Thin Layer Chromatography Method for Identification and Quantification of Oleanolic Acid in the Roots of Achyranthes aspera Linn.|
Aim: There is a link between biological activities and secondary metabolite presence in plants. A chromatographic method using HPTLC for the detection and quantification of oleanolic acid from the roots of Achyranthes aspera Linn is being developed and validated as part of the present research work. Methods: In current research, the External Standard Method is […]
Accelerated Stability Study in Alternative Formulations of a Second- Generation Biopharmaceutical Product
Filgrastim, a stimulating factor of the granulocyte colony (G-CSF), is a hematopoietic glycoprotein that binds to neutrophil precursor cells of the bone marrow with high affinity to its receptors, thereby inducing neutrophil proliferation and differentiation. There is a brief half-life for the first-generation commercial product (between 3.5 and 3.8 hours). However, by means of a […]
Medicinal Plant Mucuna pruriens: From Farm to Pharma
Mucuna pruriens, commonly known in India as Kaucha, is well-known for its neuroprotective and aphrodisiac properties and has been widely used since ancient times in the Indian Ayurveda System for the preparation of herbal formulations and tonics. Compared to other legumes, Mucuna seeds have a higher amount of L-Dopa and is a promising medication in […]
An Update of the Situation about the Protection of Inventions Derived from Plant Research in a Megadiverse Country: The Case of Mexico
This paper discusses the current situation in Mexico, a nation rich in plant species, regarding the poor security of industrial land. In addition, indigenous peoples have used plant species medicinally, and significant research is also being carried out on plant products. The security of industrial property remains a problem that has recently been implemented into […]
Anti-inflammatory and Anti-leukaemic Activities of the Kigelia africana Stem Bark, Fruit and Leaf Extracts
Cancer is one of the deadliest diseases currently ravaging and destroying humans and even animals, and exerts its high range of pathophysiological effects through the uncontrolled and irregular growth of cells that occur at various sites of the body. Leukaemia is a cancer of the blood or bone marrow that affects the haemopoietic compartment of […]