The researchers wanted to explore how vitamin E administration altered the GH-insulin–IGF-1 axis in Murrah buffaloes throughout the transition period. The Murrah buffaloes (n = 12) were selected during late gestation from the National Dairy Research Institute (NDRI) cattle herd and put into two groups of six each. The control diet was fed to group I buffaloes, while group II buffaloes were given 2000 IU/day/head vitamin E along with the control feed. By jugular veinpuncture, blood samples were taken from each buffalo at weekly intervals from day -21 to day +21 relative to parturition. A bovine specific ELISA test kit was used to measure growth hormone (GH), IGF-1, and insulin. According to the data, there was no significant difference in insulin and GH concentrations in the blood during the transition phase between the two groups. In Group I, however, the fall in insulin and IGF-I was substantially greater. The decrease in these hormone levels during the transition period was discovered to be a physiological event associated to a negative energy balance. During the changeover period, dietary supplementation with Vitamin E had no influence on peripheral hormone levels.

Author (s) Details

Bhabesh Mili
Dairy Cattle Physiology Division, National Dairy Research Institute, Karnal, Haryana, India.

Sujata Pandita
Dairy Cattle Physiology Division, National Dairy Research Institute, Karnal, Haryana, India.

B. S. Bharath Kumar
Dairy Cattle Physiology Division, National Dairy Research Institute, Karnal, Haryana, India.

Mehtab S. Parmar
Physiology and Climatology Division, Indian Veterinary Research Institute, Izatnagar, India.

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