Month: May 2021

4-N-(7-Chloroquinolin-4-yl)-1-N,1-N-diethyl petane- 1,4-diamine Ti Complex: Synthesis and Characterization

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Aims: Chloroquine is a member of the 4-aminoquinoline medication class that is used to prevent and cure malaria in locations where the disease is known to be susceptible to its effects. Metals can form covalent bonds with carbon in most cases, resulting in metal-organic complexes. Our goal is to synthesize the chloroquine–titanium complex and investigate […]

Formulation and in-vitro Evaluation of Theophylline Floating Tablets

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The application of technology’s principles to overcome medication formulation issues and the presentation of selected potently beneficial medications has been promoted as technology continues to gain traction in the medical sciences. Our team used a synthetic polymer to create a floating drug delivery system for theophylline hydrochloride and then investigated the influence of polymer concentration […]

Investigation on Phytochemical Constituents and Antimicrobial Activity of Methanolic Extract of Sonneratia apetala Buch-Ham. Areal Parts

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The purpose of this work was to investigate the phytochemical contents and antibacterial activity of methanolic extracts of Sonneratia apetala arial sections. The phytochemical contents of methanolic extracts of S. apetal included terpenoid, steroid, alkaloid, flavonoid, tannins, saponins, and polysaccharide. The antibacterial properties of plant extracts were evaluated using the well diffusion method. In varied […]

Phytochemical Examination and Hepatoprotective Impact of Stem Bark of Oroxylum indicum (L) Vent. on Carbon Tetrachloride Induced Hepatotoxicity in Rat

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Oroxylum indicum bark extracts are being studied to see if they have any hepatoprotective properties (L.) The hepatoprotective effect of petroleum ether, chloroform, methanolic, and aqueous extracts of O. indicum against carbon tetrachloride-induced liver injury in mice was investigated using silymarin as a control. The extracts’ phytochemical content was determined. SGOT, SGPT, and ALP (Serum […]

An Investigation of Anti-atopic Dermatitis Activity of Oroxylum indicum Extract Incorporated Cream

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The hunt for plant-based remedies for atopic dermatitis (AD), a recurrent dermatological disorder with a high prevalence in tropical areas, has always piqued interest. Oroxylum indicum Linn (Bignoniaceae) is a commonly used medicinal plant that has not yet been scientifically proven to be useful in the treatment of Alzheimer’s disease. The goal of this study […]

Recent Development and Validation of RP-HPLC Method for Simultaneous Estimation of Grazoprevir and Elbasvir in Bulk and Pharmaceutical Dosage Form

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Pharmaceutical analysis is a part of practical chemistry that entails a number of procedures for identifying, determining, quantifying, and purifying a substance, as well as the separation of the components of a solution or mixture and the determination of chemical compound structure. As a result, method validation is an important part of the measures that […]

Research on Production and Characterization of Alpha Cellulose Derived from Rice Straw (Oryza sativa L.)

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Rice straw may be used to produce alpha cellulose, according to research. Alpha cellulose was made by macerating rice straw with ethanol, delignifying with 3.5 percent sodium hydroxide, extracting alpha cellulose with 17.5 percent sodium hydroxide, and bleaching with hydrogen peroxide percent. In this work, the physicochemical properties of alpha cellulose were assessed and compared […]

Recent Development and Validation of Bisacodyl Analysis Method in Tablet with Absorbance Method and Area under Curves Method in Ultraviolet Spectrophotometry

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A precise, reliable, rapid, and inexpensive simple approach for the analysis of bisacodyl tablets has been devised and validated using UV spectrophotometry with absorbance technique and area under the curve. This process is carried out in a 0.1 N hydrochloric acid solvent at a maximal absorption wavelength of 263.60 nm and a region under the […]