The emergence of corporate governance has tremendously improved the business working environment since its inception in the world, and in Tanzania, in particular. The dramatic change of social and economic environment is the fruits of the development of corporate governance around the world. The concept of corporate governance has attracted researchers’ attention over the last […]
Antimicrobials are the synthetic molecules obtained from natural sources are widely used against pathogenic microbes. The improper use of these antimicrobial agents has resulted in multi-drug resistance property among various pathogens and is a great threat to the global population. Also, the spread of these resistant microbes is a great challenge to the medical practitioners. […]
Anti-carcinogenic Effects of the Flavonoid Luteolin Luteolin may be a flavonoid that is a component of our daily nutrition in comparatively low amounts (less than one mg/day). withal, some medical specialty studies counsel AN inverse correlation between luteolin intake and also the risk of some cancer sorts. Luteolin displays specific medication and anti-carcinogenic effects, which […]
Nonperturbative two-dimensional quantum gravity We propose a nonperturbative definition of two-dimensional quantum gravity, supported a double-scaling limit of the random-matrix model. we tend to derive a particular equation for the partition operate of two-dimensional gravity coupled to conformal matter as a function of the string coupling constant that governs the genus growth of two-dimensional surfaces, […]
Aims: To examine the properties of hydrazide compounds shown to inhibit Mycobacterium tuberculosis. To identify properties that affect efficiency of bacterial inhibition. Study Design: Utilizing data from previous studies of compounds that inhibit Mycobacterium tuberculosis, then statistical and pattern recognition methods are applied to identify interrelationships. Place and Duration of Study: Department of Chemistry, Durham […]
Prodrug design can be used in the following cases: improving active drug solubility and consequently bioavailability, increasing permeability and absorption and modifying the drug’s distribution profile. In the prodrug design, a computational approach consisting of calculations using Molecular Orbital (MO) and Molecular Mechanics (MM) methods and correlations between experimental and calculated values can be utilized. […]
Background: Family medicine (FM) physicians are bound to providing healthcare services at a variety of clinical and community settings. They should be equipped to competently handle health emergencies in a multitude of professional procedures. Medical education on patients often raises safety issues; simulation-based medical education (SBME) was a solution enabling education in a risk free […]
This study aims to review the spectrum of thyroid diseases in Makurdi, Benue State of Nigeria through a histopathological survey. It is a retrospective study covering 1st January, 2005 to 31st December, 2016. Ninety four (94) consecutive cases of thyroidectomy specimens collected from Holy Trinity Specialist Hospital, Makurdi, Nigeria a private hospital and Benue State […]
The association between chronic inflammatory disease and cancer has been well established through years of research. In corollary, progressive resistance to chimeric monoclonal antibodies has been reported in literature. The purpose of this investigation was to establish the overall trend of the chimeric monoclonal antibody (Infliximab) failure compared with human monoclonal antibody (Adalimumab). It was […]
Prodrug is a term used to define a pharmacologically inactive chemical entity that can be used to temporarily alter the physicochemical properties of a drug to increase its usefulness and decrease its associated toxicity. According to the definition, the inactive prodrug converts to its active parent drug and a non-toxic linker upon exposure to a […]
