A Narrative Review on the Effect of Acetaminophen and Ibuprofen in Orthodontic Tooth Movement

Application of orthodontic force causes an inflammatory event resulting in bone resorption and subsequent orthodontic tooth movement (OTM) in the periodontium. The release of inflammatory mediators such as E2 prostaglandins and Interleukin-1β serve as potent bone resorption stimulators. Strong force application results in discomfort and the same non-steroidal anti-inflammatory medications (NSAIDs) are recommended for relief. […]