An Efficient and Industrially Scalable Total Synthesis of Anti-Alzheimer Drug Donepezil

Alzheimer’s disease is a progressive neurodegenerative disease that begins slowly and worsens over time. Individuals with Alzheimer’s disease experience a reversal of mental health roles, leaving them incapacitated and unable to perform everyday activities. The elderly are the ones that are most often affected by this disease. However, research suggests that people as young as […]

Possible Approaches for the Treatment of Alzheimer’s Disease through Analysis of Patent Documents

Alzheimer’s disease (AD) is the most common cause of dementia and, as a consequence of increased lifespan and consequent population aging, is becoming increasingly prevalent. It is a chronic, progressive, and hitherto incurable neurodegenerative condition. Dysfunction of the beta-amyloid protein (Aβ) and microtubule-associated protein tau, resulting in neuronal degeneration, is associated with the main neuropathological […]

Alzheimer’s Disease: A Chronic Infection

Alzheimer’s disease ( AD) has been shown to be a chronic spirochete-origin infection over the past few years. As most other bacteria, these spirochetes form biofilms; in addition, the biofilms contribute to both the chronicity and pathogenesis of the disease in large measure. The microbes become undetectable and resistant to the immune system and to […]