Glaucoma may be an autoimmune disease

Glaucoma, a sickness that afflicts nearly seventy million folks worldwide, are some things of a mystery despite its prevalence. very little is thought concerning the origins of the sickness, that damages the membrane and second cranial nerve and might cause cecity.

A new study from university Associate in Nursing Massachusetts Eye and Ear has found that eye disease could, of course, be a disease. in a very study of mice, the researchers showed that the body’s own T cells are to blame for the progressive retinal degeneration seen in eye disease. [1]

Retina and glaucoma: surgical complications

Background: The shut structural and microcirculatory co-relation between the anterior and posterior segments of eye build them terribly susceptible to complications once one in each of them is affected surgically. With the appearance of anti-fibrotic agents within the management of eye disease, the rates of vitreoretinal complications became additional frequently. [2]

A Metabolomics Profiling of Glaucoma Points to Mitochondrial Dysfunction, Senescence, and Polyamines Deficiency

Purpose: to see the plasma metabolomic signature of primary glaucoma (POAG).

Methods: we tend to compare the metabolomic profiles of plasma from people with POAG (n = 36) with age- and sex-matched controls with cataract (n = 27). A targeted metabolomics study was performed victimization the standardized p180 Biocrates Absolute IDQ p180 kit with a QTRAP 5500 spectroscopy. variable analyses were performed victimization principal element analysis (PCA) and therefore the least absolute shrinkage and choice operator (LASSO) methodology. [3]

Application of Pattern Recognition Analysis to Optimize Hemifield Asymmetry Patterns for Early Detection of Glaucoma

Purpose: To assess the diagnostic utility of a brand new hemifield spatial property analysis derived victimization pattern recognition distinction sensitivity isocontours (CSIs) at intervals the Humphrey Field Analyzer (HFA) 24-2 field of regard (VF) take a look at the grid. The performance of associate degree best CSI-derived map was compared against a commercially out there bunch technique (Glaucoma Hemifield take a look at, GHT).

Methods: 5 hundred VF results of 116 healthy subjects were accustomed confirm normative distribution limits for comparisons. Pattern recognition analysis was applied to HFA 24-2 sensitivity information to see CSI theme maps delineating clusters for hemifield comparisons. [4]

Health Workers Awareness and Knowledge of Glaucoma in Tertiary Hospital in Birnin Kebbi, Nigeria

Background: eye disease is a crucial public ill health. best causes of irreversible visual impairment and second causes of visual impairment worldwide. eye disease progresses slowly with few or no noticeable symptoms within the early stage therefore several patients gift in advanced stage initially hospital visitation.

Glaucoma-related visual impairment is merely evitable with early detection and treatment, it’s imperative to search out well people within the target population. Public awareness and information of eye disease play a necessary role in preventing visual impairment and improve quality of life of eye disease patients.

Aim: to understand the extent of awareness and information of eye disease among medical experts during a tertiary hospital in the North-western Federal Republic of Nigeria. [5]

Reference

[1] Glaucoma may be an autoimmune disease

Date: August 10, 2018, Source: Massachusetts Institute of Technology (web link)

[2] Retina and glaucoma: surgical complications

Sahoo NK, Balijepalli P, Singh SR, Jhingan M, Senthil S, Chhablani J. Retina and glaucoma: surgical complications. International Journal of Retina and Vitreous. 2018 Dec 1;4(1):29. (web link)

[3] A Metabolomics Profiling of Glaucoma Points to Mitochondrial Dysfunction, Senescence, and Polyamines Deficiency

Leruez S, Marill A, Bresson T, de Saint Martin G, Buisset A, Muller J, Tessier L, Gadras C, Verny C, Gohier P, Amati-Bonneau P. A Metabolomics Profiling of Glaucoma Points to Mitochondrial Dysfunction, Senescence, and Polyamines Deficiency. Investigative Ophthalmology & Visual Science. 2018 Sep 4;59(11):4355-61. (web link)

[4] Application of Pattern Recognition Analysis to Optimize Hemifield Asymmetry Patterns for Early Detection of Glaucoma

Phu J, Khuu SK, Bui BV, Kalloniatis M. Application of Pattern Recognition Analysis to Optimize Hemifield Asymmetry Patterns for Early Detection of Glaucoma. Translational Vision Science & Technology. 2018 Sep 4;7(5):3-. (web link)

[5] Health Workers Awareness and Knowledge of Glaucoma in Tertiary Hospital in Birnin Kebbi, Nigeria

  1. F. Monsudi1*, E. S. Saka1, and A. O. Ayodapo2

1Department of Ophthalmology, Federal Medical Centre, Birnin Kebbi, Kebbi State, Nigeria.

2Department of Family Medicine, Federal Medical Centre, Birnin Kebbi, Kebbi State, Nigeria. (web link)

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