Scientists design new skin cell culture technique to study human papillomavirus

A new cell culture strategy guarantees to illuminate the mysterious early stages of human papillomavirus (HPV) infection, in line with analysis revealed in PLOS Pathogens by Malgorzata Bienkowska-Haba and colleagues at LA State University.

Most HPV infections cause no symptoms, however bound varieties of HPV square measure related to cervical, throat, and different cancers. HPV infects skin cells referred to as keratinocytes before they need absolutely matured, or differentiated, and square measure still dividing into new cells. [1]

Development of a Survey to Examine the Association between Relationship Status and Human Papillomavirus Vaccination Behavior

Literature: HPV is that the most prevailing STI in us. though an immunizing agent to stop HPV infection exists, only 49.5% of females were up-to-date on the suggested vaccination HPV vaccination series in 2016. tho’ suggested for younger people, there’s a catch-up amount for females ages 18-26, that shows consistent under-participation. One potential risk issue for non-vaccination could also be relationship standing. in contrast to alternative sexual health problems wherever monogynic, long-run relationships function a protecting issue, such relationships could negatively impact HPV infection risk perception. Building on the previous qualitative analysis, this study examined the quantitative association between relationship standing and HPV vaccination behavior. [2]

IMPORTANCE OF HIGH-RISK HUMAN PAPILLOMAVIRUS INFECTION DETECTION IN FEMALE RENAL TRANSPLANT RECIPIENTS IN THE FIRST YEAR AFTER TRANSPLANTATION

OBJECTIVES: Most of the human papillomavirus (HPV) infections square measure “cleared” by the system, however, in cases of system suppression infections may lead to the development of malignancies. The aim of this study was to seek out out the frequency of HR-HPV infection in early amount when excretory organ transplantation in Latvian recipients receiving immunological disorder medical care and to follow the progression of the infection up to at least one year. METHODS: forty-three feminine excretory organ recipients (median age of forty-eight IQR= 39-58) and seventy-nine much healthy feminine people (median age of forty-eight IQR= 42-57) as a sway cluster were listed during this investigation. For the detection of HPV infection patients’ samples (blood and channel swabs) wherever collected time period when transplantation with the following assortment of six months and one year. [3]

Trends in Risks for Second Primary Cancers Associated With Index Human Papillomavirus–Associated Cancers

Importance within the last four decades, survival among patients with human papillomavirus (HPV)–associated cancers have improved, whereas the incidence of those cancers has accrued among younger cohorts. Among survivors of HPV-associated cancers, persistent HPV infection might stay a risk issue for preventable HPV-associated second primary cancers (HPV-SPCs).

Objectives to research the chance of HPV-SPCs among survivors of HPV-associated index cancers and to check the hypothesis that the HPV-SPC risk among these persons has accrued over the last four decades. [4]

Specific Human Papillomavirus Genotypes Isolated from Cervical Cancer Specimens in Calabar, Nigeria

Aim: to work out specific human papillomavirus genotypes isolated from cervical cancer specimens in Calabar, Nigeria.

Study Design: this can be a cross-sectional study of repository paraffin-embedded tissue block of invasive cervical cancer specimen.

Study Place and Period: This study was done in the department of pathology, University of Calabar Teaching Hospital, Calabar for cervical cancer specimen between Jan 2006 and Dec 2014.

Methodology: Paraffin-embedded tissue block of invasive cervical cancer specimen from the study amount (January 2006 to Dec 2014) were collected. Primary socio-demographic information was obtained from medical records within the department (such as surgical pathology register, histopathology request forms). Sections of the tissue were obtained from the blocks. The DNA (DNA) was extracted and an enzyme chain reaction was done. Then desoxyribonucleic acid accelerator immunochemical assay and reverse conjugation line probe assay were performed for human papillomavirus desoxyribonucleic acid detection and specific HPV genotyping. [5]

Reference

[1] Scientists design new skin cell culture technique to study human papillomavirus

Date: March 1, 2018, Source: PLOS (web link)

[2] Development of a Survey to Examine the Association between Relationship Status and Human Papillomavirus Vaccination Behavior

Waters A. Development of a Survey to Examine the Association between Relationship Status and Human Papillomavirus Vaccination Behavior. (web link)

[3] IMPORTANCE OF HIGH-RISK HUMAN PAPILLOMAVIRUS INFECTION DETECTION IN FEMALE RENAL TRANSPLANT RECIPIENTS IN THE FIRST YEAR AFTER TRANSPLANTATION

Cistjakovs M, Sultanova A, Jermakova O, Sokolovska L, Chapenko S, Lesina-Korne B, Rozental R, Murovska M, Ziedina I. IMPORTANCE OF HIGH-RISK HUMAN PAPILLOMAVIRUS INFECTION DETECTION IN FEMALE RENAL TRANSPLANT RECIPIENTS IN THE FIRST YEAR AFTER TRANSPLANTATION. (web link)

[4] Trends in Risks for Second Primary Cancers Associated With Index Human Papillomavirus–Associated Cancers

Suk R, Mahale P, Sonawane K, Sikora AG, Chhatwal J, Schmeler KM, Sigel K, Cantor SB, Chiao EY, Deshmukh AA. Trends in Risks for Second Primary Cancers Associated With Index Human Papillomavirus–Associated Cancers. JAMA Network Open. 2018 Sep 7;1(5):e181999-. (web link)

[5] Specific Human Papillomavirus Genotypes Isolated from Cervical Cancer Specimens in Calabar, Nigeria

Godstime I. Irabor1*, Dominic Akpan2, Ejemen Aigbe3, Kenneth A. Omoruyi4, Uche Amaechi5, Ayodele J. Omotoso4 and Martin A. Nnoli4

1Department of Pathology, Saba University School of Medicine, Saba, Netherlands.

2Department of Laboratory Medicine and Pathobiology, University of Toronto, Ontario, Canada.

3Irrua Specialist Teaching Hospital, Irrua, Edo State, Nigeria.

4Department of Pathology, University of Calabar Teaching Hospital, Calabar, Nigeria.

5Department of Internal Medicine, Lagos University Teaching Hospital, Lagos, Nigeria. (web link)

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