Study on Kuwait Environmental Remediation Program (KERP): Remediation Demonstration Strategy

Iraqi troops exploded 798 oil wells in Kuwait’s desert, causing 114 square kilometres of damage. Crude oil gushed from the shattered oil wells, forming lakes that contaminated almost 40 square kilometres of land. Wet and dry oil reservoirs were built in low-lying sections of the desert to limit the spread of oil, and polluted soil […]

Advances in Chemistry and Biomedical Applications of Plasma Immersion Ion Implantation Treatments of Titanium Using Monte Carlo Simulations (Stop and Range Ions in Matter)

The surface modification of a titanium alloy via plasma immersion ion implantation was investigated in this study in order to increase its tribological qualities such as hardness and scratch resistance. Furthermore, the thickness of changed layers was investigated using physical simulation utilising SRIM (stopping and range ions in matter). Nanoindentation and XPS investigations of ti6al4v […]

Bucillamine as An Efficient H Atom Donor Protects High-Molar-Mass Hyaluronan from Oxidative Degradation by Effective Scavenging of Free Radicals

Bucillamine has been shown to preserve high-molecular-mass hyaluronan from degradation caused by a free-radical-generating system containing cupric ions and ascorbate. We adopted a multimodal strategy in this investigation, employing a range of methodologies such as non-isothermal chemiluminometry, thermogravimetry, and differential scanning calorimetry to characterise the hyaluronan fragments produced. Bucillamine was found to significantly slow the […]

Chaperone-like Activity and Quaternary Structure Dynamics of HSPB5 in Crowded Milieu

Small heat-shock proteins (sHSPs) are ATP-independent molecular chaperones that engage with partially unfolded proteins to avoid abnormal aggregation, demonstrating chaperone-like activity in the process. The chaperone-like activity of sHSPs is influenced by the dynamics of the quaternary structure. The link between the dynamic structure of sHSPs and their chaperone-like activity, on the other hand, is […]

Determination of Human Wharton’s Jelly Mesenchymal Stem Cell-Mediated Sciatic Nerve Recovery Associated with Upregulation of Regulatory T Cells

Peripheral nerve injuries are distinct from central nervous system (CNS) injuries, which often affect end-target organs and can result in denervation and function loss. For functional nerve healing, it’s critical to speed up peripheral nerve regeneration. The direct upregulation and release of neurotrophic factors by human Wharton’s jelly-derived mesenchymal stem cells (hWJ-MSC) promotes sciatic nerve […]

Studies on Anti-Inflammatory and General Glucocorticoid Physiology in Skeletal Muscles Affected by Duchenne Muscular Dystrophy: An approach towards Exploration of Steroid-Sparing Agents

The activation of proinflammatory and metabolic biological pathways in skeletal muscle cells is a hallmark of Duchenne muscular dystrophy (DMD). The dystrophin-associated protein complex, a large transmembrane protein complex that acts as a shock absorber during muscle contraction, a receiver and transducer of cellular signals, and a scaffold for signalling proteins, is destabilised in the […]

Determination of Telmisartan and Hydrochlorothiazide Using HPTLC in Human Plasma: Development and Validation of Bioanalytical Method

A simple, sensitive, quick, and cost-effective thin layer chromatographic technique was used to determine the concentrations of telmisartan and hydrochlorothiazide in human plasma using paracetamol as an internal reference. A combination of hydrochlorothiazide (HCT) and telmisartan (TEL) is more successful than either medicine alone in the treatment of hypertension. The plasma sample was collected using […]

Study on the Characteristics of α-Chymotrypsin Folding Intermediates by Hydrophobic Interaction Chromatography (HIC)

The study of protein folding intermediates is crucial for understanding the folding mechanism of denatured proteins and enhancing protein folding efficiency. A new methodology to define the intermediate of urea-denatured -chymotrypsin (-Chy) was established in this study by using some of the linear parameters of the stoichiometric displacement theory of retention of solute (SDT-R) of […]

Influence of the Pre-Treatment and Post-Treatment Operations on the Surface Chemistry and Corrosion Behavior of Cerium-Based Conversion Coatings on Aluminum

We studied the corrosion-protective properties of Cerium oxide coatings chemically deposited in green Ce solution conversion on technically pure aluminium (Al 1050) that were then immersed in phosphate solutions. The effect of: the kind of pretreatment of the l substrate; the conversion treatment of the l substrate in е-containing or P-containing solutions; and the sequential […]

The Greatest Error in Biological Sciences, Started in 1930 and Continuing Up to Now, Generating Numerous Profound Misunderstandings in Almost All Fields of Biology

Is a cell a complex coacervate with distribution coefficients and adsorption coefficients as the primary physical–chemical characteristics, allowing for low-entropy bioenergetics based on coherence, as Schrödinger proposed in 1944? Is it possible that a cell contains ordinary water in solution with tiny solutes like K+, separated by a membrane containing ion-pumps that must constantly combat […]