Organokinetics for Transient Cytomegalovirus Infection in Mice

The basic level of CMV diffusion into mouse organs was identified, as well as its relevance. This was conducted prior to our involvement in a larger project examining the immunological and molecular aspects of MCMV infection pathogenesis in Balb/c mice. We may have created potential to produce one or more vaccinations against the virus as […]

Cadmium Induced Nephrotoxicity in Adult Male Albino Mice

Cadmium is a contemporary hazardous metal that is released into the atmosphere, hydrosphere, and soil as a by-product of zinc and lead mining and processing, resulting in environmental degradation. The kidney is the organ most impacted by chronic cadmium exposure in humans. The goal of this study was to see what effects intraperitoneal acute administration […]

Coryphantha macromeris Cell Suspension Cultures: Phytochemical Profiling and Agitation Velocity Effect on Cell Morphology and Viability

For the generation of active plant metabolites, cell suspension cultures are a viable option. The agitation velocity is one of the most important factors in achieving high cell viability and metabolite yields. The effect of agitation velocity on cell viability and morphology of Coryphantha macromeris cell suspension cultures was investigated in this study, and the […]

Ethnobotanical Study of Medicinal Utilization and Phytochemical Analysis of Baobab Tree (Adansonia digitata L.) in Zaria Local Government Area of Kaduna State, Nigeria

Traditional medicine encompasses a diverse range of remedies and practises that differ by culture and location. The medicinal use and phytochemical composition of the Baobab tree (Adansonia digitata L.) in Kaduna State’s Zaria Local Government Area were investigated. Each of the six (6) districts received twenty (20) surveys at random, for a total of one […]

The Medicinal Importance of Hydrocotyle asiatica Linn. in Kaduna North Local Government Area of Kaduna State, Nigeria

Ayurvedic medicine, traditional African medicine, and traditional Chinese medicine all employ Hydrocotyl asiatica (L.) as a therapeutic herb. In Nigeria, however, little is known regarding its medicinal application. In order to pick 10 marketers and 40 herbal practitioners, a multistage sampling methodology was used. Hydrocotyle asiatica water extract has anti-inflammatory and anti-filarial properties, and is […]

Mitochondrial Involvement in the Molecular Mechanisms of Ischemia-Reperfusion Injury in the Heart

Mitochondria are responsible for maintaining cell viability and essential biological activities by producing energy (ATP). These organelles are also a major source of reactive oxygen species (ROS) and a number of apoptosis inducers. The importance of mitochondria in a variety of areas of cell physiology and pathology, such as intracellular signaling, has been demonstrated. Mitochondria […]

The Role of Cytoskeletal Proteins in the Regulation of Mitochondrial Function

Understanding muscle bioenergetics requires identifying mitochondrial roles and regulatory mechanisms, which is a key challenge in physiology/pathophysiology. Microtubules, intermediate filaments, and microfilaments are three cytoskeletal structures that play a critical role in mitochondrial structure/architecture, intracellular organisation, and motility. Furthermore, various cytoskeleton-mitochondrial contacts can actively contribute to the regulation of mitochondrial respiratory activity and oxidative phosphorylation […]

Pigment Production in Callus Culture of ‘Karandafi’ Red Sorghum (Sorghum bicolor (L.) Moench). A Probable Cure for Sickle Cell Anaemia

‘Karandafi’ is a sorghum landrace having antisickling properties and high levels of 3-deoxyanthocyanidin, however it is mutant in nature. This tends to impede large-scale manufacture of this key medication for sickle cell anaemia treatment. Sorghum bicolor is high in phytochemicals, and its extract is used to treat sickle cell anaemia in combination with other medicinal […]

Seasonal Variations of Some Physicochemical Parameters of the Brackish Water Farm, Buguma, Niger Delta, Nigeria

The brackish water fish farm in Buguma, Nigerian Institute for Oceanography and Marine Research/African Regional Aquaculture Centre (NIOMR/ARAC), is an example of tidal water between the farm and nearby stream, where tidal water flows into and out, enhancing continual water exchange. The water quality parameter expresses the composition of water as it is influenced by […]

Studies on Biology of Hadda Beetle, Epilachna vigintioctopunctata: A Serious Pest of Wild Beeter Gourd, Momordica dioica

Beetles have a substantial economic impact for two reasons. When there are a lot of them, plant feeders become a pest of farm crops and forest trees. Predatory species, on the other hand, play an important role in man’s efforts to manage plant-feeding pests. Pests are animals whose populations have grown to the point that […]